The ἔκδοσις package by Robert Alessi joined the TeXLive distribution this week.  ekdosis is a LuaLaTeX package designed for producing multilingual critical editions.  I haven't tried it, but it seems promising to me, both for its clear input syntax and its TEI output possibilities.  I am emotionally attached to EDMAC, of course.  But this deserves a look:

Professor Dominik Wujastyk

Singhmar Chair in Classical Indian Society and Polity

University of Alberta, Canada

South Asia at the U of A: