Thanks, Hans. Combined Characters such as
m̆ should survive through multiple transmissions across different platforms, as long as the applications utilized are fully compatible with Unicode.
Technically speaking, I believe the problems you have had with your wonderful volume are not really single-glyph characters vs. multi-glyph characters, but Unicode vs. non-Unicode. As you may know, the standard for extended Latin characters predates Unicode. For example, ISO 8859-1 includes many commonly used symbols for Indological transliteration such as Ā, ā, Ē, ē, Ī, ī, Ō, ō, Ū, ū was first published in March 1985. Many non-Unicode applications support these extended Latin characters, and therefore you find them survive through multiple transmissions (Unicode is compatible with these Latin extensions as well).
However, many of the new characters added for the Unicode standard, will not survive through the use of non-Unicode applications, whether they are single glyph or multi-glyph. For example, Ḃ (Latin Capital Letter B with dot above) is a single glyph character, but I am pretty sure it will not survive transmission through non-Unicode applications (let's see how many find Ḃ in their emails correctly).
Alas, until the computing world rids itself of all pestiferous non-Unicode applications, perhaps, we will have to deal with the headaches of diacritics!
Suresh.